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Resource Coding Colonoscopies

A colonoscopy is a screening test that can help detect colon cancer or pre-cancer. The earlier signs of colon cancer are detected, the easier it is to prevent or treat the disease.

A screening test is a test provided to a patient in the absence of signs or symptoms. A screening colonoscopy is a service performed on an asymptomatic person for the purpose of testing for the presence of colorectal cancer or colorectal polyps. Whether a polyp or cancer is ultimately found does not change the screening intent of that procedure. As part of the Affordable Care Act (ACA), Medicare and most third-party payors are required to cover services given an A or B rating by the U.S. Preventive Services Task Force (USPSTF) without a co-pay or deductible, but the correct CPT and ICD-10-CM codes must be submitted to trigger coverage at 100% for the patient.

Diagnostic colonoscopy is a test performed as a result of an abnormal finding, sign or symptom (such as abdominal pain, bleeding, diarrhea, etc.). Medicare and most commercial payors do not waive the co-pay and deductible when the intent of the visit is to perform a diagnostic colonoscopy.

The CPT code for a colonoscopy without biopsy or other interventions is 45378.

This code is used for commercial and Medicaid patients.

The HCPCS code for a screening colonoscopy for a Medicare patient is G0105.

The ICD-10-CM diagnosis code for a screening colonoscopy is Z12.11. This code can be used for reimbursement purposes.

Other CPT codes for colonoscopies include:
  • 45380 – Colonoscopy with biopsy
  • 45381 – Colonoscopy with directed submucosal injection
  • 45382 – Colonoscopy with control of bleeding
For commercial and Medicaid patients, use CPT code 45378 (Colonoscopy, flexible, proximal to splenic flexure; diagnostic, with or without collection of specimen(s) by brushing or washing, with or without colon decompression [separate procedure]). However, if polyps are removed use the appropriate CPT code below based on the removal technique:

  • 45380 – Colonoscopy, flexible; with biopsy, single or multiple
  • 45384 – Colonoscopy, flexible; with removal of tumor(s), polyp(s), or other lesion(s) by hot biopsy forceps
  • 45385 – Colonoscopy, flexible; with removal of tumor(s), polyp(s), or other lesion(s) by snare technique
  • 45388 – Colonoscopy, flexible; with ablation of tumor(s), polyp(s), or other lesion(s) (includes pre- and post-dilation and guide wire passage, when performed)
Add modifier 33 (preventive services) to each CPT code submitted on the claim. If modifier 33 is not added, the colonoscopy will not be recognized as a screening service and the patient will be inappropriately billed.

For Medicare beneficiaries who choose colonoscopy as their colorectal cancer screening, use Healthcare Common Procedural Coding System (HCPCS) code G0105 (Colorectal cancer screening; colonoscopy on individual at high risk) or G0121 (Colorectal cancer screening; colonoscopy on individual not meeting the criteria for high risk) as appropriate. CMS developed the HCPCS codes to differentiate between screening and diagnostic colonoscopies in the Medicare population. If polyps are removed, use the appropriate CPT code listed above and add modifier PT (colorectal cancer screening test; converted to diagnostic test or other procedure) to each CPT code for Medicare. If modifier PT is not added to the CPT code submitted on the Medicare claim, the colonoscopy with polypectomy will not be recognized as a screening service and the patient will be inappropriately billed.

Medicare beneficiaries without high risk factors are eligible for screening colonoscopy every 10 years. Beneficiaries at high risk for developing colorectal cancer are eligible once every 24 months. Medicare considers an individual at high risk for developing colorectal cancer as one who has one or more of the following:

  • A close relative (sibling, parent or child) who has had colorectal cancer or an adenomatous polyp.
  • A family history of familial adenomatous polyposis.
  • A family history of hereditary nonpolyposis colorectal cancer.
  • A personal history of adenomatous polyps.
  • A personal history of colorectal cancer.
  • Inflammatory bowel disease, including Crohn’s disease and ulcerative colitis.




Billing and Coding: Diagnostic and Therapeutic Colonoscopy

CPT codes

CodeDescription
44388COLONOSCOPY THROUGH STOMA; DIAGNOSTIC, INCLUDING COLLECTION OF SPECIMEN(S) BY BRUSHING OR WASHING, WHEN PERFORMED (SEPARATE PROCEDURE)
44389COLONOSCOPY THROUGH STOMA; WITH BIOPSY, SINGLE OR MULTIPLE
44390COLONOSCOPY THROUGH STOMA; WITH REMOVAL OF FOREIGN BODY(S)
44391COLONOSCOPY THROUGH STOMA; WITH CONTROL OF BLEEDING, ANY METHOD
44392COLONOSCOPY THROUGH STOMA; WITH REMOVAL OF TUMOR(S), POLYP(S), OR OTHER LESION(S) BY HOT BIOPSY FORCEPS
44394COLONOSCOPY THROUGH STOMA; WITH REMOVAL OF TUMOR(S), POLYP(S), OR OTHER LESION(S) BY SNARE TECHNIQUE
44401COLONOSCOPY THROUGH STOMA; WITH ABLATION OF TUMOR(S), POLYP(S), OR OTHER LESION(S) (INCLUDES PRE-AND POST-DILATION AND GUIDE WIRE PASSAGE, WHEN PERFORMED)
44402COLONOSCOPY THROUGH STOMA; WITH ENDOSCOPIC STENT PLACEMENT (INCLUDING PRE- AND POST-DILATION AND GUIDE WIRE PASSAGE, WHEN PERFORMED)
44404COLONOSCOPY THROUGH STOMA; WITH DIRECTED SUBMUCOSAL INJECTION(S), ANY SUBSTANCE
44405COLONOSCOPY THROUGH STOMA; WITH TRANSENDOSCOPIC BALLOON DILATION
44406COLONOSCOPY THROUGH STOMA; WITH ENDOSCOPIC ULTRASOUND EXAMINATION, LIMITED TO THE SIGMOID, DESCENDING, TRANSVERSE, OR ASCENDING COLON AND CECUM AND ADJACENT STRUCTURES
44407COLONOSCOPY THROUGH STOMA; WITH TRANSENDOSCOPIC ULTRASOUND GUIDED INTRAMURAL OR TRANSMURAL FINE NEEDLE ASPIRATION/BIOPSY(S), INCLUDES ENDOSCOPIC ULTRASOUND EXAMINATION LIMITED TO THE SIGMOID, DESCENDING, TRANSVERSE, OR ASCENDING COLON AND CECUM AND ADJACENT STRUCTURES
45378COLONOSCOPY, FLEXIBLE; DIAGNOSTIC, INCLUDING COLLECTION OF SPECIMEN(S) BY BRUSHING OR WASHING, WHEN PERFORMED (SEPARATE PROCEDURE)
45379COLONOSCOPY, FLEXIBLE; WITH REMOVAL OF FOREIGN BODY(S)
45380COLONOSCOPY, FLEXIBLE; WITH BIOPSY, SINGLE OR MULTIPLE
45381COLONOSCOPY, FLEXIBLE; WITH DIRECTED SUBMUCOSAL INJECTION(S), ANY SUBSTANCE
45382COLONOSCOPY, FLEXIBLE; WITH CONTROL OF BLEEDING, ANY METHOD
45384COLONOSCOPY, FLEXIBLE; WITH REMOVAL OF TUMOR(S), POLYP(S), OR OTHER LESION(S) BY HOT BIOPSY FORCEPS
45385COLONOSCOPY, FLEXIBLE; WITH REMOVAL OF TUMOR(S), POLYP(S), OR OTHER LESION(S) BY SNARE TECHNIQUE
45386COLONOSCOPY, FLEXIBLE; WITH TRANSENDOSCOPIC BALLOON DILATION
45388COLONOSCOPY, FLEXIBLE; WITH ABLATION OF TUMOR(S), POLYP(S), OR OTHER LESION(S) (INCLUDES PRE- AND POST-DILATION AND GUIDE WIRE PASSAGE, WHEN PERFORMED)
45389COLONOSCOPY, FLEXIBLE; WITH ENDOSCOPIC STENT PLACEMENT (INCLUDES PRE- AND POST-DILATION AND GUIDE WIRE PASSAGE, WHEN PERFORMED)
45391COLONOSCOPY, FLEXIBLE; WITH ENDOSCOPIC ULTRASOUND EXAMINATION LIMITED TO THE RECTUM, SIGMOID, DESCENDING, TRANSVERSE, OR ASCENDING COLON AND CECUM, AND ADJACENT STRUCTURES
45392COLONOSCOPY, FLEXIBLE; WITH TRANSENDOSCOPIC ULTRASOUND GUIDED INTRAMURAL OR TRANSMURAL FINE NEEDLE ASPIRATION/BIOPSY(S), INCLUDES ENDOSCOPIC ULTRASOUND EXAMINATION LIMITED TO THE RECTUM, SIGMOID, DESCENDING, TRANSVERSE, OR ASCENDING COLON AND CECUM, AND ADJACENT STRUCTURES
45393COLONOSCOPY, FLEXIBLE; WITH DECOMPRESSION (FOR PATHOLOGIC DISTENTION) (EG, VOLVULUS, MEGACOLON), INCLUDING PLACEMENT OF DECOMPRESSION TUBE, WHEN PERFORMED


 

ICD-10-CM Codes that Support Medical Necessity​


CodeDescription
A04.3Enterohemorrhagic Escherichia coli infection
A04.5Campylobacter enteritis
A04.71Enterocolitis due to Clostridium difficile, recurrent
A04.72Enterocolitis due to Clostridium difficile, not specified as recurrent
A06.0Acute amebic dysentery
A06.1Chronic intestinal amebiasis
A06.2Amebic nondysenteric colitis
A06.9Amebiasis, unspecified
A18.31Tuberculous peritonitis
A18.32Tuberculous enteritis
A41.01Sepsis due to Methicillin susceptible Staphylococcus aureus
A41.02Sepsis due to Methicillin resistant Staphylococcus aureus
A41.4Sepsis due to anaerobes
A41.50Gram-negative sepsis, unspecified
A41.51Sepsis due to Escherichia coli [E. coli]
A41.52Sepsis due to Pseudomonas
A41.53Sepsis due to Serratia
A41.59Other Gram-negative sepsis
A41.81Sepsis due to Enterococcus
A41.89Other specified sepsis
A42.7Actinomycotic sepsis
C18.0Malignant neoplasm of cecum
C18.1Malignant neoplasm of appendix
C18.2Malignant neoplasm of ascending colon
C18.3Malignant neoplasm of hepatic flexure
C18.4Malignant neoplasm of transverse colon
C18.5Malignant neoplasm of splenic flexure
C18.6Malignant neoplasm of descending colon
C18.7Malignant neoplasm of sigmoid colon
C18.8Malignant neoplasm of overlapping sites of colon
C19Malignant neoplasm of rectosigmoid junction
C20Malignant neoplasm of rectum
C21.0Malignant neoplasm of anus, unspecified
C21.1Malignant neoplasm of anal canal
C21.2Malignant neoplasm of cloacogenic zone
C21.8Malignant neoplasm of overlapping sites of rectum, anus and anal canal
C45.1Mesothelioma of peritoneum
C46.4Kaposi's sarcoma of gastrointestinal sites
C48.1Malignant neoplasm of specified parts of peritoneum
C48.2Malignant neoplasm of peritoneum, unspecified
C48.8Malignant neoplasm of overlapping sites of retroperitoneum and peritoneum
C49.4Malignant neoplasm of connective and soft tissue of abdomen
C49.A4Gastrointestinal stromal tumor of large intestine
C49.A9Gastrointestinal stromal tumor of other sites
C7A.020Malignant carcinoid tumor of the appendix
C7A.021Malignant carcinoid tumor of the cecum
C7A.022Malignant carcinoid tumor of the ascending colon
C7A.023Malignant carcinoid tumor of the transverse colon
C7A.024Malignant carcinoid tumor of the descending colon
C7A.025Malignant carcinoid tumor of the sigmoid colon
C7A.026Malignant carcinoid tumor of the rectum
C7A.029Malignant carcinoid tumor of the large intestine, unspecified portion
C76.2Malignant neoplasm of abdomen
C76.3Malignant neoplasm of pelvis
C78.5Secondary malignant neoplasm of large intestine and rectum
C78.6Secondary malignant neoplasm of retroperitoneum and peritoneum
C78.7Secondary malignant neoplasm of liver and intrahepatic bile duct
C80.2Malignant neoplasm associated with transplanted organ
D01.0Carcinoma in situ of colon
D01.1Carcinoma in situ of rectosigmoid junction
D01.2Carcinoma in situ of rectum
D01.3Carcinoma in situ of anus and anal canal
D12.0Benign neoplasm of cecum
D12.1Benign neoplasm of appendix
D12.2Benign neoplasm of ascending colon
D12.3Benign neoplasm of transverse colon
D12.4Benign neoplasm of descending colon
D12.5Benign neoplasm of sigmoid colon
D12.6Benign neoplasm of colon, unspecified
D12.7Benign neoplasm of rectosigmoid junction
D12.8Benign neoplasm of rectum
D12.9Benign neoplasm of anus and anal canal
D3A.020Benign carcinoid tumor of the appendix
D3A.021Benign carcinoid tumor of the cecum
D3A.022Benign carcinoid tumor of the ascending colon
D3A.023Benign carcinoid tumor of the transverse colon
D3A.024Benign carcinoid tumor of the descending colon
D3A.025Benign carcinoid tumor of the sigmoid colon
D3A.026Benign carcinoid tumor of the rectum
D3A.029Benign carcinoid tumor of the large intestine, unspecified portion
D37.3Neoplasm of uncertain behavior of appendix
D37.4Neoplasm of uncertain behavior of colon
D37.5Neoplasm of uncertain behavior of rectum
D37.8Neoplasm of uncertain behavior of other specified digestive organs
D50.0Iron deficiency anemia secondary to blood loss (chronic)
D50.9Iron deficiency anemia, unspecified
E34.0Carcinoid syndrome
E44.0Moderate protein-calorie malnutrition
I33.0Acute and subacute infective endocarditis
I78.0Hereditary hemorrhagic telangiectasia
 
K50.00Crohn's disease of small intestine without complications
K50.011Crohn's disease of small intestine with rectal bleeding
K50.012Crohn's disease of small intestine with intestinal obstruction
K50.013Crohn's disease of small intestine with fistula
K50.014Crohn's disease of small intestine with abscess
K50.018Crohn's disease of small intestine with other complication
K50.10Crohn's disease of large intestine without complications
K50.111Crohn's disease of large intestine with rectal bleeding
K50.112Crohn's disease of large intestine with intestinal obstruction
K50.113Crohn's disease of large intestine with fistula
K50.114Crohn's disease of large intestine with abscess
K50.118Crohn's disease of large intestine with other complication
K50.80Crohn's disease of both small and large intestine without complications
K50.811Crohn's disease of both small and large intestine with rectal bleeding
K50.812Crohn's disease of both small and large intestine with intestinal obstruction
K50.813Crohn's disease of both small and large intestine with fistula
K50.814Crohn's disease of both small and large intestine with abscess
K50.818Crohn's disease of both small and large intestine with other complication
K51.00Ulcerative (chronic) pancolitis without complications
K51.011Ulcerative (chronic) pancolitis with rectal bleeding
K51.012Ulcerative (chronic) pancolitis with intestinal obstruction
K51.013Ulcerative (chronic) pancolitis with fistula
K51.014Ulcerative (chronic) pancolitis with abscess
K51.018Ulcerative (chronic) pancolitis with other complication
K51.20Ulcerative (chronic) proctitis without complications
K51.211Ulcerative (chronic) proctitis with rectal bleeding
K51.212Ulcerative (chronic) proctitis with intestinal obstruction
K51.213Ulcerative (chronic) proctitis with fistula
K51.214Ulcerative (chronic) proctitis with abscess
K51.218Ulcerative (chronic) proctitis with other complication
K51.30Ulcerative (chronic) rectosigmoiditis without complications
K51.311Ulcerative (chronic) rectosigmoiditis with rectal bleeding
K51.312Ulcerative (chronic) rectosigmoiditis with intestinal obstruction
K51.313Ulcerative (chronic) rectosigmoiditis with fistula
K51.314Ulcerative (chronic) rectosigmoiditis with abscess
K51.318Ulcerative (chronic) rectosigmoiditis with other complication
K51.40Inflammatory polyps of colon without complications
K51.411Inflammatory polyps of colon with rectal bleeding
K51.412Inflammatory polyps of colon with intestinal obstruction
K51.413Inflammatory polyps of colon with fistula
K51.414Inflammatory polyps of colon with abscess
K51.418Inflammatory polyps of colon with other complication
K51.50Left sided colitis without complications
K51.511Left sided colitis with rectal bleeding
K51.512Left sided colitis with intestinal obstruction
K51.513Left sided colitis with fistula
K51.514Left sided colitis with abscess
K51.518Left sided colitis with other complication
K51.80Other ulcerative colitis without complications
K51.811Other ulcerative colitis with rectal bleeding
K51.812Other ulcerative colitis with intestinal obstruction
K51.813Other ulcerative colitis with fistula
K51.814Other ulcerative colitis with abscess
K51.818Other ulcerative colitis with other complication
 
K52.0Gastroenteritis and colitis due to radiation
K52.1Toxic gastroenteritis and colitis
K52.21Food protein-induced enterocolitis syndrome
K52.22Food protein-induced enteropathy
K52.29Other allergic and dietetic gastroenteritis and colitis
K52.3Indeterminate colitis
K52.81Eosinophilic gastritis or gastroenteritis
K52.82Eosinophilic colitis
K52.831Collagenous colitis
K52.832Lymphocytic colitis
K52.838Other microscopic colitis
K52.89Other specified noninfective gastroenteritis and colitis
K55.031Focal (segmental) acute (reversible) ischemia of large intestine
K55.032Diffuse acute (reversible) ischemia of large intestine
K55.039Acute (reversible) ischemia of large intestine, extent unspecified
K55.041Focal (segmental) acute infarction of large intestine
K55.1Chronic vascular disorders of intestine
K55.20Angiodysplasia of colon without hemorrhage
K55.21Angiodysplasia of colon with hemorrhage
K55.8Other vascular disorders of intestine
K56.0Paralytic ileus
K56.1Intussusception
K56.2Volvulus
K56.3Gallstone ileus
K56.41Fecal impaction
K56.49Other impaction of intestine
K56.50Intestinal adhesions [bands], unspecified as to partial versus complete obstruction
K56.51Intestinal adhesions [bands], with partial obstruction
K56.52Intestinal adhesions [bands] with complete obstruction
K56.690Other partial intestinal obstruction
K56.691Other complete intestinal obstruction
K56.699Other intestinal obstruction unspecified as to partial versus complete obstruction
K57.20Diverticulitis of large intestine with perforation and abscess without bleeding
K57.21Diverticulitis of large intestine with perforation and abscess with bleeding
K57.30Diverticulosis of large intestine without perforation or abscess without bleeding
K57.31Diverticulosis of large intestine without perforation or abscess with bleeding
K57.32Diverticulitis of large intestine without perforation or abscess without bleeding
K57.33Diverticulitis of large intestine without perforation or abscess with bleeding
K57.40Diverticulitis of both small and large intestine with perforation and abscess without bleeding
K57.41Diverticulitis of both small and large intestine with perforation and abscess with bleeding
K57.50Diverticulosis of both small and large intestine without perforation or abscess without bleeding
K57.51Diverticulosis of both small and large intestine without perforation or abscess with bleeding
K57.52Diverticulitis of both small and large intestine without perforation or abscess without bleeding
K57.53Diverticulitis of both small and large intestine without perforation or abscess with bleeding
K59.1Functional diarrhea
K59.2Neurogenic bowel, not elsewhere classified
K59.81Ogilvie syndrome
K59.89Other specified functional intestinal disorders
K62.0Anal polyp
K62.1Rectal polyp
K62.2Anal prolapse
K62.3Rectal prolapse
K62.4Stenosis of anus and rectum
K62.5Hemorrhage of anus and rectum
K62.6Ulcer of anus and rectum
K62.7Radiation proctitis
K62.81Anal sphincter tear (healed) (nontraumatic) (old)
K62.89Other specified diseases of anus and rectum
K63.1Perforation of intestine (nontraumatic)
K63.2Fistula of intestine
K63.3Ulcer of intestine
K63.4Enteroptosis
K63.5Polyp of colon
K63.81Dieulafoy lesion of intestine
K63.89Other specified diseases of intestine
K64.0First degree hemorrhoids
K64.1Second degree hemorrhoids
K64.2Third degree hemorrhoids
K64.3Fourth degree hemorrhoids
K64.4Residual hemorrhoidal skin tags
K64.5Perianal venous thrombosis
K64.8Other hemorrhoids
K64.9Unspecified hemorrhoids
K90.1Tropical sprue
K91.89Other postprocedural complications and disorders of digestive system
K92.1Melena
K92.2Gastrointestinal hemorrhage, unspecified
K92.89Other specified diseases of the digestive system
L83Acanthosis nigricans
Q42.8Congenital absence, atresia and stenosis of other parts of large intestine
Q85.81PTEN tumor syndrome
Q85.82Other Cowden syndrome
Q85.83Von Hippel-Lindau syndrome
Q85.89Other phakomatoses, not elsewhere classified
R10.0Acute abdomen
R10.11Right upper quadrant pain
R10.12Left upper quadrant pain
R10.13Epigastric pain
R10.2Pelvic and perineal pain
R10.31Right lower quadrant pain
R10.32Left lower quadrant pain
R10.33Periumbilical pain
R10.84Generalized abdominal pain
R11.13Vomiting of fecal matter
R19.4Change in bowel habit
R19.5Other fecal abnormalities
R19.7Diarrhea, unspecified
R19.8Other specified symptoms and signs involving the digestive system and abdomen
R71.0Precipitous drop in hematocrit
R93.3Abnormal findings on diagnostic imaging of other parts of digestive tract
 
T18.3XXAForeign body in small intestine, initial encounter
T18.3XXDForeign body in small intestine, subsequent encounter
T18.3XXSForeign body in small intestine, sequela
T18.4XXAForeign body in colon, initial encounter
T18.4XXDForeign body in colon, subsequent encounter
T18.4XXSForeign body in colon, sequela
Z85.020Personal history of malignant carcinoid tumor of stomach
Z85.030Personal history of malignant carcinoid tumor of large intestine
Z85.038Personal history of other malignant neoplasm of large intestine
Z85.040Personal history of malignant carcinoid tumor of rectum
Z85.048Personal history of other malignant neoplasm of rectum, rectosigmoid junction, and anus
Z85.05Personal history of malignant neoplasm of liver
Z85.060Personal history of malignant carcinoid tumor of small intestine
Z85.110Personal history of malignant carcinoid tumor of bronchus and lung
Z85.230Personal history of malignant carcinoid tumor of thymus
Z85.520Personal history of malignant carcinoid tumor of kidney
Z85.821Personal history of Merkel cell carcinoma
Z86.004Personal history of in-situ neoplasm of other and unspecified digestive organs
Z86.010Personal history of colonic polyps
Z87.19Personal history of other diseases of the digestive system
 
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